N-[6-chloro-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-2-pyridinyl]butanamide

InChIKey	`CRKQBJZCCHKEGI-UHFFFAOYSA-N`
Compound Name	N-[6-chloro-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-2-pyridinyl]butanamide
Canonical SMILES	`CCCC(=O)Nc1cc(-c2c[nH]c3ncccc23)cc(Cl)n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	20
Pfam Stratification	Cross-Family
Avg pChEMBL	7.03
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O00311	CDC7	Homo sapiens	Human	PF00069	9.1	Ki	ChEMBL
P49336	CDK8	Homo sapiens	Human	PF00069	8.1	Ki	ChEMBL
Q9HAZ1	CLK4	Homo sapiens	Human	PF00069	8.1	Ki	ChEMBL
Q9Y463	DYRK1B	Homo sapiens	Human	PF00069	7.8	Ki	ChEMBL
Q13627	DYRK1A	Homo sapiens	Human	PF00069	7.6	Ki	ChEMBL
O75116	ROCK2	Homo sapiens	Human	PF25346 PF00069 PF08912	7.4	Ki	ChEMBL
Q8N4C8	MINK1	Homo sapiens	Human	PF00780 PF00069	7.0	Ki	ChEMBL
Q9H2X6	HIPK2	Homo sapiens	Human	PF00069	7.0	Ki	ChEMBL
Q00535	CDK5	Homo sapiens	Human	PF00069	6.9	Ki	ChEMBL
Q14680	MELK	Homo sapiens	Human	PF02149 PF00069 PF21594	6.9	Ki	ChEMBL
P17612	PRKACA	Homo sapiens	Human	PF00069	6.7	Ki	ChEMBL
P49760	CLK2	Homo sapiens	Human	PF00069	6.7	Ki	ChEMBL
P50750	CDK9	Homo sapiens	Human	PF00069	6.7	Ki	ChEMBL
Q5S007	LRRK2	Homo sapiens	Human	PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477	6.7	Ki	ChEMBL
O43293	DAPK3	Homo sapiens	Human	PF00069	6.5	Ki	ChEMBL
Q9UEE5	STK17A	Homo sapiens	Human	PF00069	6.5	Ki	ChEMBL
P50613	CDK7	Homo sapiens	Human	PF00069	6.4	Ki	ChEMBL
P17948	FLT1	Homo sapiens	Human	PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854	6.2	Ki	ChEMBL
O95819	MAP4K4	Homo sapiens	Human	PF00780 PF00069	6.1	Ki	ChEMBL
P51817	PRKX	Homo sapiens	Human	PF00069	6.1	Ki	ChEMBL