Molecule Details
| InChIKey | CQNWMZNUZDLOBT-YRNVUSSQSA-N |
|---|---|
| Compound Name | 1-[(3,5-dichloro-4-pyridinyl)methyl]-6-methoxy-5-[(E)-5-phenylpent-1-enyl]phthalazine |
| Canonical SMILES | COc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1/C=C/CCCc1ccccc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.72 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 7.7 | IC50 | ChEMBL |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 7.7 | IC50 | ChEMBL;BindingDB |
| Q08493 | PDE4C | Homo sapiens | Human | PF18100 PF00233 | 7.7 | IC50 | ChEMBL |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 7.7 | IC50 | ChEMBL |