Molecule Details
| InChIKey | CQKMMXFWQMPMFC-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({4-[3-(piperidin-1-yl)propoxy]phenyl}amino)pyrimidin-4-yl]carbamate |
| Canonical SMILES | COc1ccc(N(C(=O)Oc2c(C)cccc2C)c2ccnc(Nc3ccc(OCCCN4CCCCC4)cc3)n2)c(OC)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.87 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P06239 | LCK | Homo sapiens | Human | PF07714 PF00017 PF00018 | 9.0 | IC50 | BindingDB |
| P12931 | SRC | Homo sapiens | Human | PF07714 PF00017 PF00018 | 8.2 | IC50 | BindingDB |
| P35968 | KDR | Homo sapiens | Human | PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 | 6.5 | IC50 | BindingDB |