Molecule Details
InChIKeyCPGKMMMSMJKHDL-UHFFFAOYSA-N
Compound Name2-(1h-Indazol-5-yl)imidazo[1,2-a]pyrimidine
Canonical SMILESc1cnc2nc(-c3ccc4[nH]ncc4c3)cn2c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)16
Pfam Stratification Homologous
Avg pChEMBL6.5
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (16)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.9 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 7.5 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 7.0 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.8 Ki ChEMBL;BindingDB
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.7 Ki ChEMBL;BindingDB
O00311 CDC7 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q9NR20 DYRK4 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 6.2 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.1 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.1 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.0 Ki ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 6.0 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.0 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.0 Ki ChEMBL