Molecule Details
| InChIKey | COWNEZLXLGOWIV-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-(3-((((2-Chlorobenzyl)amino)carbonyl)amino)-2-thienyl)-5,6-dihydroxypyrimidine-4-carboxylic acid |
| Canonical SMILES | O=C(NCc1ccccc1Cl)Nc1ccsc1-c1nc(O)c(O)c(C(=O)O)n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.17 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (2)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q8JXU8 | NS5B | Hepacivirus hominis | Pathogen | PF00998 | 7.3 | IC50 | BindingDB |
| P26664 | Hepatitis C virus genotype 1a (isolate 1) | Pathogen | PF07652 PF01543 PF01542 PF01539 PF01560 PF01538 PF01006 PF01001 PF01506 PF08300 PF08301 PF12941 PF22027 PF02907 PF00998 | 7.0 | IC50 | ChEMBL;BindingDB |