Molecule Details
InChIKeyCOLCNDRDBCLVOC-ICSRJNTNSA-N
Canonical SMILESCc1nc[nH]c1CN1CCN(C(=O)N[C@@H](CC(C)C)C(=O)O)[C@@H](Cc2ccccc2)C1=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL8.02
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB18125
Drug NamePTX-100
CAS Number501010-06-6
Groups investigational
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 50496833 CHEMBL3218390 ChemSpider: 9714256
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P49354 FNTA Homo sapiens Human PF01239 8.0 IC50 ChEMBL;BindingDB
P53609 PGGT1B Homo sapiens Human PF00432 8.0 IC50 ChEMBL
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P49354 FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha modulator targets
P49356 FNTB Protein farnesyltransferase subunit beta modulator targets