Molecule Details
InChIKeyCOGUZYALRYMQTD-LJQANCHMSA-N
Compound NameCID 145749888
Canonical SMILESC=CC(=O)Nc1ccc(C(=O)N2CCC[C@@H](Nc3ncc(SCc4ncc(C(C)(C)C)o4)s3)C2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.0
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9NYV4 CDK12 Homo sapiens Human PF00069 7.6 IC50 ChEMBL;BindingDB
O75909 CCNK Homo sapiens Human PF00134 PF21797 7.5 IC50 ChEMBL
Q14004 CDK13 Homo sapiens Human PF00069 7.3 IC50 ChEMBL;BindingDB
O60563 CCNT1 Homo sapiens Human PF00134 PF21797 6.9 IC50 ChEMBL;BindingDB
P50750 CDK9 Homo sapiens Human PF00069 6.9 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.9 IC50 ChEMBL;BindingDB
P78396 CCNA1 Homo sapiens Human PF02984 PF00134 PF16500 6.9 IC50 ChEMBL
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 6.4 IC50 ChEMBL;BindingDB
Q00526 CDK3 Homo sapiens Human PF00069 6.4 IC50 ChEMBL