Molecule Details
| InChIKey | CNOWOXXSYNLOJR-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-(4-fluorophenyl)-5-(furan-3-yl)-N-[[4-(hydroxycarbamoyl)phenyl]methyl]-1H-pyrrole-2-carboxamide |
| Canonical SMILES | O=C(NO)c1ccc(CNC(=O)c2[nH]c(-c3ccoc3)cc2-c2ccc(F)cc2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.2 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P43116 | PTGER2 | Homo sapiens | Human | PF00001 | 9.0 | Ki | ChEMBL;BindingDB |
| Q9UBN7 | HDAC6 | Homo sapiens | Human | PF00850 PF02148 | 7.4 | IC50 | ChEMBL;BindingDB |
| Q9BY41 | HDAC8 | Homo sapiens | Human | PF00850 | 6.9 | IC50 | BindingDB |
| Q13547 | HDAC1 | Homo sapiens | Human | PF00850 | 6.4 | IC50 | BindingDB |
| O15379 | HDAC3 | Homo sapiens | Human | PF00850 | 6.3 | IC50 | BindingDB |