Molecule Details
InChIKeyCMVHFGNTABZQJU-HCXYKTFWSA-N
Compound NameBms-813160
Canonical SMILESCC(=O)N[C@@H]1C[C@H](NC(C)(C)C)CC[C@@H]1N1CC[C@H](Nc2ncnc3cc(C(C)(C)C)nn23)C1=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.38
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB16240
Drug NameBMS-813160
CAS Number1286279-29-5
Groups investigational
ATC Codes nan
DescriptionBMS-813160 is under investigation in clinical trial NCT03496662 (BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)).

Categories: Cardiovascular Agents
Cross-references: ChemSpider: 71061479
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P51681 CCR5 Homo sapiens Human PF00001 8.4 IC50 ChEMBL;BindingDB
P41597 CCR2 Homo sapiens Human PF00001 8.3 IC50 ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P41597 CCR2 C-C chemokine receptor type 2 modulator targets
P51681 CCR5 C-C chemokine receptor type 5 modulator targets