(2S,3aS,4R,9bR)-4-(4-hydroxyphenyl)-2-(trifluoromethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol

InChIKey	`CLYUNXJFERDYMU-VHWLVUOQSA-N`
Compound Name	(2S,3aS,4R,9bR)-4-(4-hydroxyphenyl)-2-(trifluoromethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol
Canonical SMILES	`Oc1ccc([C@@H]2Oc3ccc(O)cc3[C@@H]3C[C@H](C(F)(F)F)C[C@@H]32)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	8.84
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	9.2	pIC50	TTD_MultiTarget
Q92731	ESR2	Homo sapiens	Human	PF12497 PF00104 PF00105	9.2	Ki	ChEMBL;BindingDB
P03372	ESR1	Homo sapiens	Human	PF12743 PF00104 PF02159 PF00105	7.9	Ki	ChEMBL;BindingDB
Q96WX4	erg6	Pneumocystis carinii (strain B80)	Pathogen	PF08241 PF08498	9.2	pIC50	TTD_MultiTarget