Molecule Details
InChIKeyCLSJNXXMIVKULC-MUUNZHRXSA-N
Canonical SMILESCOc1ccc(CCOC(c2ccccc2)(c2ccccc2)[C@H](Oc2nc(C)cc(C)n2)C(=O)O)cc1OC
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.5
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB20151
Drug NameFeloprentan
CAS Number204267-34-5
Groups experimental
ATC Codes nan
DescriptionFeloprentan is a small molecule drug. The usage of the INN stem '-entan' in the name indicates that Feloprentan is a endothelin receptor antagonist. Feloprentan has a monoisotopic molecular weight of 528.23 Da.

Categories: Acids, Acyclic Endothelin Receptor Antagonists Fatty Acids Fatty Acids, Volatile Lipids Stereoisomerism
Cross-references: BindingDB: 50079424 CHEMBL316735 ZINC: ZINC000001488192
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P25101 EDNRA Homo sapiens Human PF00001 8.7 Ki ChEMBL;BindingDB
P24530 EDNRB Homo sapiens Human PF00001 8.3 Ki ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P24530 EDNRB Endothelin receptor type B antagonist targets
P25101 EDNRA Endothelin-1 receptor antagonist targets