Molecule Details
| InChIKey | CLJZLDBGGLGZDB-LPTQZCDUSA-N |
|---|---|
| Compound Name | (1S,5S,6R)-10-(3,5-dichlorophenyl)sulfonyl-5-(methoxymethyl)-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one |
| Canonical SMILES | COC[C@H]1CN(Cc2ccccn2)C(=O)[C@@H]2CCC[C@H]1N2S(=O)(=O)c1cc(Cl)cc(Cl)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.16 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P62942 | FKBP1A | Homo sapiens | Human | PF00254 | 9.3 | Ki | ChEMBL |
| P68106 | FKBP1B | Homo sapiens | Human | PF00254 | 8.9 | Ki | ChEMBL |
| Q02790 | FKBP4 | Homo sapiens | Human | PF00254 PF00515 PF07719 | 7.7 | Ki | ChEMBL |
| Q13451 | FKBP5 | Homo sapiens | Human | PF00254 PF00515 PF13181 | 7.6 | Ki | ChEMBL |
| P26885 | FKBP2 | Homo sapiens | Human | PF00254 | 7.2 | Ki | ChEMBL |