US9611277, Example 76 — MultiTargetDB

InChIKey	`CLEHSUGXBFEAJH-UHFFFAOYSA-N`
Compound Name	US9611277, Example 76
Canonical SMILES	`Cc1ccc(-n2nccn2)c(C(=O)N2CC3CCC2C(Oc2ccc(C(F)(F)F)cn2)C3)n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.6
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O43613	HCRTR1	Homo sapiens	Human	PF00001	8.5	Ki	ChEMBL;BindingDB
O43614	HCRTR2	Homo sapiens	Human	PF00001 PF03827	6.7	Ki	ChEMBL;BindingDB