(3Z)-3-[(E)-3-(4-aminophenyl)prop-2-enylidene]-1H-indol-2-one

InChIKey	`CKGUJEHCLFSIPS-FLUHZAPOSA-N`
Compound Name	(3Z)-3-[(E)-3-(4-aminophenyl)prop-2-enylidene]-1H-indol-2-one
Canonical SMILES	`Nc1ccc(/C=C/C=C2\C(=O)Nc3ccccc32)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.35
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P10636	MAPT	Homo sapiens	Human	PF00418	7.4	Ki	ChEMBL;BindingDB
P37840	SNCA	Homo sapiens	Human	PF01387	7.3	Ki	ChEMBL;BindingDB
P05067	APP	Homo sapiens	Human	PF10515 PF12924 PF12925 PF02177 PF03494 PF00014	7.3	Ki	ChEMBL;BindingDB