InChIKey	CJOFXWAVKWHTFT-XSFVSMFZSA-N
Compound Name	Fluvoxamine
Canonical SMILES	COCCCC/C(=N\OCCN)c1ccc(C(F)(F)F)cc1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.18
Source	BindingDB;ChEMBL

DrugBank ID	DB00176
Drug Name	Fluvoxamine
CAS Number	54739-18-3
Groups	approved investigational
ATC Codes	N06AB08
Description	Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder. Fluvoxamine has been in use in clinical practice since 1983 and has a clin...

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Categories: Amines Anti-Anxiety Agents Antidepressive Agents Antidepressive Agents Indicated for Depression Antidepressive Agents, Second-Generation BSEP/ABCB11 Substrates Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP1A2 Inhibitors (strong) Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 CYP2B6 Inhibitors Cytochrome P-450 CYP2B6 Inhibitors (strength unknown) Cytochrome P-450 CYP2C19 Inhibitors Cytochrome P-450 CYP2C19 Inhibitors (strong) Cytochrome P-450 CYP2C9 Inhibitors Cytochrome P-450 CYP2C9 Inhibitors (moderate) Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (moderate) Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (moderate) Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A7 Inhibitors Cytochrome P-450 CYP3A7 Inhibitors (moderate) Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Drugs that are Mainly Renally Excreted Enzyme Inhibitors Hydroxylamines Hypoglycemia-Associated Agents Membrane Transport Modulators Nervous System Neurotransmitter Agents Neurotransmitter Uptake Inhibitors Oximes P-glycoprotein inhibitors Psychoanaleptics Psychotropic Drugs Selective Serotonin Reuptake Inhibitors Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome Serotonin Agents Serotonin Modulators Tranquilizing Agents

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Cross-references: BindingDB: 50028091 ChEBI: 5138 CHEMBL814 ChemSpider: 4481878 Drugs Product Database (DPD): 1212 C07571 PDB: FVX PharmGKB: PA449690 PubChem:3404 PubChem:46507588 RxCUI: 42355 Therapeutic Targets Database: DNC000897 Wikipedia: Fluvoxamine ZINC: ZINC000003872605