Molecule Details
InChIKeyCJLMANFTWLNAKC-UHFFFAOYSA-N
Compound NameK02288
Canonical SMILESCOc1cc(-c2cc(-c3cccc(O)c3)cnc2N)cc(OC)c1OC
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL7.28
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
P37023 ACVRL1 Homo sapiens Human PF07714 PF08515 8.7 IC50 ChEMBL
P36894 BMPR1A Homo sapiens Human PF01064 PF07714 PF08515 7.5 IC50 ChEMBL
Q04771 ACVR1 Homo sapiens Human PF01064 PF07714 PF08515 7.5 IC50 ChEMBL;BindingDB
P36897 TGFBR1 Homo sapiens Human PF01064 PF00069 PF08515 6.5 IC50 ChEMBL;BindingDB
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 6.2 IC50 ChEMBL;BindingDB