InChIKey	CIDUJQMULVCIBT-MQDUPKMGSA-N
Compound Name	Netilmicin
Canonical SMILES	CCN[C@@H]1C[C@H](N)[C@@H](O[C@H]2OC(CN)=CC[C@H]2N)[C@H](O)[C@H]1O[C@H]1OC[C@](C)(O)[C@H](NC)[C@H]1O
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	55
Pfam Stratification	Cross-Family
Avg pChEMBL	7.7
Source	ChEMBL

DrugBank ID	DB00955
Drug Name	Netilmicin
CAS Number	56391-56-1
Groups	approved
ATC Codes	S01AA23 J01GB07
Description	Netilmicin is a semisynthetic 1-N-ethyl derivative of sisomycin, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity. Netilmicin inhibits protein synthesis in susceptible organisms by binding to the bacterial 30S ribosomal subunit and interfering with mRN...

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Categories: Agents that produce neuromuscular block (indirect) Aminoglycoside Antibacterials Anti-Bacterial Agents Anti-Infective Agents Antibacterials for Systemic Use Antiinfectives for Systemic Use Carbohydrates Drugs that are Mainly Renally Excreted Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index Enzyme Inhibitors Gentamicins Glycosides Narrow Therapeutic Index Drugs Nephrotoxic agents Ophthalmologicals Protein Synthesis Inhibitors Sensory Organs

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Cross-references: BindingDB: 50470664 ChEBI: 7528 CHEMBL1572 ChemSpider: 20152952 Drugs Product Database (DPD): 8353 C07657 D08268 PharmGKB: PA164754913 PubChem:441306 PubChem:46507404 RxCUI: 7337 Therapeutic Targets Database: DAP000404 Wikipedia: Netilmicin ZINC: ZINC000052981502