5-(6-benzothiazolylmethylene)-3,5-dihydro-2-(((1S)-1-(methoxymethyl)-3-methylbutyl)amino)-4H-Imidazol-4-one, (5Z)-

InChIKey	`CHQYAWLKOUOTQO-QVYJARAXSA-N`
Compound Name	5-(6-benzothiazolylmethylene)-3,5-dihydro-2-(((1S)-1-(methoxymethyl)-3-methylbutyl)amino)-4H-Imidazol-4-one, (5Z)-
Canonical SMILES	`COC[C@@H](CC(C)C)NC1=N/C(=C\c2ccc3ncsc3c2)C(=O)N1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	20
Pfam Stratification	Cross-Family
Avg pChEMBL	7.39
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q8IVW4	CDKL3	Homo sapiens	Human	PF00069	9.3	IC50	ChEMBL
Q8IZX4	TAF1L	Homo sapiens	Human	PF00439 PF12157 PF09247 PF15288	9.2	IC50	ChEMBL
Q5MAI5	CDKL4	Homo sapiens	Human	PF00069	9.1	IC50	ChEMBL
Q13627	DYRK1A	Homo sapiens	Human	PF00069	8.6	IC50	ChEMBL
Q9HAZ1	CLK4	Homo sapiens	Human	PF00069	8.2	IC50	ChEMBL
Q9Y463	DYRK1B	Homo sapiens	Human	PF00069	8.1	IC50	ChEMBL
P49759	CLK1	Homo sapiens	Human	PF00069	8.1	IC50	ChEMBL
Q92519	TRIB2	Homo sapiens	Human	PF00069	7.9	IC50	ChEMBL
P49760	CLK2	Homo sapiens	Human	PF00069	7.5	IC50	ChEMBL
Q2M2I8	AAK1	Homo sapiens	Human	PF00069	7.0	IC50	ChEMBL
Q13237	PRKG2	Homo sapiens	Human	PF00027 PF00069	6.9	IC50	ChEMBL
Q92630	DYRK2	Homo sapiens	Human	PF00069	6.7	IC50	ChEMBL
P49761	CLK3	Homo sapiens	Human	PF00069	6.7	IC50	ChEMBL
O43781	DYRK3	Homo sapiens	Human	PF00069	6.5	IC50	ChEMBL
Q9NR20	DYRK4	Homo sapiens	Human	PF00069	6.5	IC50	ChEMBL
Q9H2X6	HIPK2	Homo sapiens	Human	PF00069	6.5	IC50	ChEMBL
P49841	GSK3B	Homo sapiens	Human	PF00069	6.2	Kd	ChEMBL
Q7L7X3	TAOK1	Homo sapiens	Human	PF00069	6.2	IC50	ChEMBL
Q8NE63	HIPK4	Homo sapiens	Human	PF00069	6.2	IC50	ChEMBL
Q9H422	HIPK3	Homo sapiens	Human	PF00069	6.2	IC50	ChEMBL