Molecule Details
| InChIKey | CGMJQQJSWIRRRL-UHFFFAOYSA-N |
|---|---|
| Compound Name | Phenazepam |
| Canonical SMILES | O=C1CN=C(c2ccccc2Cl)c2cc(Br)ccc2N1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 9.96 |
| Source | ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB19164 |
|---|---|
| Drug Name | Phenazepam |
| CAS Number | 51753-57-2 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Phenazepam is under investigation in clinical trial NCT03017430 (Pregabalin for Opiate Withdrawal Syndrome). |
Categories: Adjuvants, Immunologic Antiarrhythmic agents Anticonvulsants Benzazepines Cardiovascular Agents Central Nervous System Agents Central Nervous System Depressants GABA Agents Heterocyclic Compounds, Fused-Ring Immunologic Factors Neurotransmitter Agents
Cross-references: CHEMBL1709464 ChemSpider: 36657 PharmGKB: PA166180939 Wikipedia: Phenazepam ZINC: ZINC000000001919
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P14867 | GABRA1 | Homo sapiens | Human | PF02931 PF02932 | 10.3 | Ki | ChEMBL |
| P47869 | GABRA2 | Homo sapiens | Human | PF02931 PF02932 | 10.2 | Ki | ChEMBL |
| P18507 | GABRG2 | Homo sapiens | Human | PF02931 PF02932 | 10.1 | Ki | ChEMBL |
| P47870 | GABRB2 | Homo sapiens | Human | PF02931 PF02932 | 10.1 | Ki | ChEMBL |
| P34903 | GABRA3 | Homo sapiens | Human | PF02931 PF02932 | 9.9 | Ki | ChEMBL |
| P31644 | GABRA5 | Homo sapiens | Human | PF02931 PF02932 | 9.2 | Ki | ChEMBL |