Molecule Details
InChIKeyCGECJCJUHCZZGO-UHFFFAOYSA-N
Compound Name4-[7-[1-[2-(Dimethylamino)ethyl]pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-2-[(3-fluorophenyl)methoxy]benzamide
Canonical SMILESCN(C)CCn1cc(-c2ccn3c(-c4ccc(C(N)=O)c(OCc5cccc(F)c5)c4)cnc3c2)cn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.38
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P51955 NEK2 Homo sapiens Human PF00069 9.0 IC50 ChEMBL;BindingDB
Q15418 RPS6KA1 Homo sapiens Human PF00069 PF00433 8.3 IC50 ChEMBL;BindingDB
Q13627 DYRK1A Homo sapiens Human PF00069 8.2 IC50 ChEMBL;BindingDB
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 7.7 IC50 ChEMBL;BindingDB
O14757 CHEK1 Homo sapiens Human PF00069 7.2 IC50 ChEMBL;BindingDB
P49841 GSK3B Homo sapiens Human PF00069 7.0 IC50 ChEMBL;BindingDB
P24941 CDK2 Homo sapiens Human PF00069 6.4 IC50 ChEMBL;BindingDB
P11802 CDK4 Homo sapiens Human PF00069 6.4 IC50 ChEMBL;BindingDB
P31749 AKT1 Homo sapiens Human PF00169 PF00069 PF00433 6.2 IC50 ChEMBL;BindingDB