Molecule Details
| InChIKey | CGDZXLJGHVKVIE-DNVCBOLYSA-N |
|---|---|
| Compound Name | Telcagepant |
| Canonical SMILES | O=C(N[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(CC(F)(F)F)C1=O)N1CCC(n2c(=O)[nH]c3ncccc32)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.9 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB12228 |
|---|---|
| Drug Name | Telcagepant |
| CAS Number | 781649-09-0 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Telcagepant has been investigated for the treatment of Migraine. It is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide involved in the pathophysiology of migraine. CGRP and its receptors are found in areas of the central and peripheral nervous system ... |
Cross-references: BindingDB: 50224431 CHEMBL236593 ChemSpider: 9494017 PDB: N7R PubChem:11319053 PubChem:347828507 Wikipedia: Telcagepant ZINC: ZINC000028827350