Molecule Details
| InChIKey | CFSQPEBVGUSQII-UHFFFAOYSA-N |
|---|---|
| Compound Name | Cra_10433 |
| Canonical SMILES | N=C(N)c1ccc2[nH]c(-c3cccc(OC4CCCC4)c3O)cc2c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.32 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB03173 |
|---|---|
| Drug Name | CRA_10433 |
| CAS Number | nan |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Cross-references: BindingDB: 50115856 CHEMBL64579 ChemSpider: 394571 PDB: CR3 PubChem:447478 PubChem:46508405 ZINC: ZINC000033360147
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00749 | PLAU | Homo sapiens | Human | PF00051 PF00089 | 6.7 | Ki | ChEMBL;BindingDB |
| P00747 | PLG | Homo sapiens | Human | PF00051 PF00024 PF00089 | 6.5 | Ki | ChEMBL;BindingDB |
| P00750 | PLAT | Homo sapiens | Human | PF00008 PF00039 PF00051 PF00089 | 6.2 | Ki | ChEMBL;BindingDB |
| P07477 | PRSS1 | Homo sapiens | Human | PF00089 | 6.2 | Ki | BindingDB |
| P00742 | F10 | Homo sapiens | Human | PF00008 PF14670 PF00594 PF00089 | 6.0 | Ki | ChEMBL;BindingDB |
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P07477 | PRSS1 | Serine protease 1 | binder | targets |