Molecule Details
| InChIKey | CFMWWZHVBLVEMM-UHFFFAOYSA-N |
|---|---|
| Compound Name | 6-(3-Methoxyphenyl)sulfanyl-5-methylthieno[2,3-d]pyrimidine-2,4-diamine |
| Canonical SMILES | COc1cccc(Sc2sc3nc(N)nc(N)c3c2C)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.38 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (2)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00374 | DHFR | Homo sapiens | Human | PF00186 | 6.1 | IC50 | ChEMBL;BindingDB |
| A0A0W4ZHR8 | Pneumocystis jirovecii (strain RU7) | Pathogen | PF00186 | 6.7 | IC50 | BindingDB |