Molecule Details
InChIKeyCFJGSVKNNIFWEA-PDGQHHTCSA-N
Canonical SMILESCCCOc1cnc(CN/C=C2\C(=O)NC(=O)c3ccc(C(C)(C)C)cc32)cc1O
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL7.0
SourceChEMBL;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
P11802 CDK4 Homo sapiens Human PF00069 7.7 IC50 ChEMBL
P24385 CCND1 Homo sapiens Human PF02984 PF00134 7.7 IC50 ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.9 pIC50 TTD_MultiTarget
P06400 RB1 Homo sapiens Human PF11934 PF01858 PF01857 PF08934 6.7 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.0 pIC50 TTD_MultiTarget