Molecule Details
InChIKeyCFBADDSSFSYJPF-UHFFFAOYSA-N
Compound Name3-methylsulfanyl-1H-1,8-phenanthrolin-4-one
Canonical SMILESCSc1cnc2c(ccc3cnccc32)c1O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)23
Pfam Stratification Cross-Family
Avg pChEMBL6.46
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (23)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13627 DYRK1A Homo sapiens Human PF00069 7.7 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 7.0 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.9 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.9 Ki ChEMBL
Q9HBY8 SGK2 Homo sapiens Human PF00069 PF00433 6.8 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.5 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.4 Ki ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.3 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.2 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.1 Ki ChEMBL
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 6.1 Ki ChEMBL
P31749 AKT1 Homo sapiens Human PF00169 PF00069 PF00433 6.1 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.1 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 6.0 Ki ChEMBL
P28482 MAPK1 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q05513 PRKCZ Homo sapiens Human PF00130 PF00564 PF00069 PF00433 6.0 Ki ChEMBL