7-nitro-N-(2H-pyrazolo[3,4-b]pyridin-3-yl)-1,2,3,4-tetrahydroacridin-9-amine

InChIKey	`CEOCITIVLDEXBN-UHFFFAOYSA-N`
Compound Name	7-nitro-N-(2H-pyrazolo[3,4-b]pyridin-3-yl)-1,2,3,4-tetrahydroacridin-9-amine
Canonical SMILES	`O=[N+]([O-])c1ccc2nc3c(c(Nc4[nH]nc5ncccc45)c2c1)CCCC3`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.33
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P22303	ACHE	Homo sapiens	Human	PF08674 PF00135	6.5	IC50	ChEMBL
P06276	BCHE	Homo sapiens	Human	PF08674 PF00135	6.4	IC50	ChEMBL
P05067	APP	Homo sapiens	Human	PF10515 PF12924 PF12925 PF02177 PF03494 PF00014	6.1	IC50	ChEMBL