Molecule Details
InChIKeyCEIJFEGBUDEYSX-FZDBZEDMSA-N
Compound NameTandospirone
Canonical SMILESO=C1[C@@H]2[C@H]3CC[C@H](C3)[C@@H]2C(=O)N1CCCCN1CCN(c2ncccn2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.65
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12833
Drug NameTandospirone
CAS Number87760-53-0
Groups investigational
ATC Codes nan
DescriptionTandospirone has been used in trials studying the treatment of Schizophrenia.

Categories: Anti-Anxiety Agents Antidepressive Agents Central Nervous System Agents Central Nervous System Depressants Heterocyclic Compounds, Fused-Ring Neurotransmitter Agents Psychotropic Drugs Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome Serotonin Agents Serotonin Receptor Agonists Tranquilizing Agents
Cross-references: BindingDB: 50099385 ChEBI: 145673 CHEMBL274047 ChemSpider: 82421 PubChem:91273 PubChem:347828999 Wikipedia: Tandospirone ZINC: ZINC000001545034
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P21917 DRD4 Homo sapiens Human PF00001 8.1 Ki ChEMBL;BindingDB
P08908 HTR1A Homo sapiens Human PF00001 7.9 Ki ChEMBL;BindingDB
P14416 DRD2 Homo sapiens Human PF00001 6.9 Ki ChEMBL;BindingDB