Molecule Details
InChIKeyCEBMEQPREMCWOL-UHFFFAOYSA-N
Compound NameN-((6,7-Difluoro-1H-benzo[d]imidazol-2-yl)methyl)-9-(3-fluorophenyl)-2-morpholino-9H-purin-6-amine
Canonical SMILESFc1cccc(-n2cnc3c(NCc4nc5c(F)c(F)ccc5[nH]4)nc(N4CCOCC4)nc32)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL6.85
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
Q14004 CDK13 Homo sapiens Human PF00069 8.0 IC50 ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 7.4 IC50 ChEMBL;BindingDB
Q9NYV4 CDK12 Homo sapiens Human PF00069 7.1 IC50 ChEMBL;BindingDB
P49674 CSNK1E Homo sapiens Human PF00069 6.6 IC50 ChEMBL;BindingDB
Q00534 CDK6 Homo sapiens Human PF00069 6.4 IC50 ChEMBL
P24385 CCND1 Homo sapiens Human PF02984 PF00134 6.3 IC50 ChEMBL
P11802 CDK4 Homo sapiens Human PF00069 6.2 IC50 ChEMBL