3-[3-methyl-1-propan-2-yl-7-[[2-(trifluoromethyl)pyridin-3-yl]methylamino]pyrazolo[4,3-b]pyridin-5-yl]-1H-pyridin-2-one

InChIKey	`CEASKHHYUJNGEA-UHFFFAOYSA-N`
Compound Name	3-[3-methyl-1-propan-2-yl-7-[[2-(trifluoromethyl)pyridin-3-yl]methylamino]pyrazolo[4,3-b]pyridin-5-yl]-1H-pyridin-2-one
Canonical SMILES	`Cc1nn(C(C)C)c2c(NCc3cccnc3C(F)(F)F)cc(-c3ccc[nH]c3=O)nc12`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.61
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q01064	PDE1B	Homo sapiens	Human	PF00233 PF08499	7.3	IC50	ChEMBL;BindingDB
P54750	PDE1A	Homo sapiens	Human	PF00233 PF08499	6.5	IC50	ChEMBL;BindingDB
Q14123	PDE1C	Homo sapiens	Human	PF00233 PF08499	6.1	IC50	ChEMBL;BindingDB