Molecule Details
| InChIKey | CDNSOMCMTZMHON-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-N-cyclohexyl-5-(1-methylpyrazol-4-yl)-2-N-[[3-(trifluoromethyl)phenyl]methyl]pyrimidine-2,4-diamine |
| Canonical SMILES | Cn1cc(-c2cnc(NCc3cccc(C(F)(F)F)c3)nc2NC2CCCCC2)cn1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.52 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q12866 | MERTK | Homo sapiens | Human | PF00041 PF00047 PF13927 PF07714 | 7.1 | IC50 | ChEMBL;BindingDB |
| P30530 | AXL | Homo sapiens | Human | PF00041 PF13927 PF07714 | 6.3 | IC50 | ChEMBL;BindingDB |
| Q06418 | TYRO3 | Homo sapiens | Human | PF00041 PF07679 PF07714 | 6.2 | IC50 | ChEMBL;BindingDB |