Molecule Details
InChIKeyCDCHESFKYUNJPV-FQEVSTJZSA-N
Compound NameCdk12-IN-E9
Canonical SMILESC=CC(=O)Nc1cccc(Nc2cc(N3CCCC[C@H]3CCO)nc3c(CC)cnn23)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL7.06
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
O60563 CCNT1 Homo sapiens Human PF00134 PF21797 7.7 IC50 ChEMBL;BindingDB
P50750 CDK9 Homo sapiens Human PF00069 7.7 IC50 ChEMBL
Q14004 CDK13 Homo sapiens Human PF00069 7.5 IC50 ChEMBL
O75909 CCNK Homo sapiens Human PF00134 PF21797 7.3 IC50 ChEMBL
Q9NYV4 CDK12 Homo sapiens Human PF00069 7.1 IC50 ChEMBL
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 6.0 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.0 IC50 ChEMBL;BindingDB