Molecule Details
InChIKeyCCASRZWPCOLUMW-GFCCVEGCSA-N
Compound Name3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-3-yl)pyridin-2-amine
Canonical SMILESC[C@@H](Oc1cc(-c2ccn(C3CCNCC3)n2)cnc1N)c1c(Cl)ccc(F)c1Cl
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL7.75
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P08581 MET Homo sapiens Human PF07714 PF01437 PF01403 PF01833 9.1 IC50 BindingDB
Q9UM73 ALK Homo sapiens Human PF12810 PF00629 PF07714 7.2 IC50 ChEMBL;BindingDB
P06748 NPM1 Homo sapiens Human PF16276 PF03066 7.0 IC50 ChEMBL