InChIKey	CBQGYUDMJHNJBX-RTBURBONSA-N
Canonical SMILES	CCOc1ccccc1O[C@H](c1ccccc1)[C@H]1CNCCO1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.77
Source	ChEMBL;BindingDB

DrugBank ID	DB00234
Drug Name	Reboxetine
CAS Number	71620-89-8
Groups	approved investigational withdrawn
ATC Codes	N06AX18
Description	Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesylate (i.e. methanesulfonate) salt is sold under tradenames including Edronax, Norebox, Prolift, Solvex, Davedax or Vestra. Reboxetine has two chiral centers, but it only exists as ...

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Categories: Adrenergic Agents Adrenergic Uptake Inhibitors Antidepressive Agents Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (weak) Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Membrane Transport Modulators Morpholines Nervous System Neurotransmitter Agents Neurotransmitter Uptake Inhibitors Oxazines P-glycoprotein inhibitors Psychoanaleptics Psychotropic Drugs

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Cross-references: BindingDB: 388642 ChEBI: 135342 CHEMBL383921 ChemSpider: 112870 PDB: 41X PharmGKB: PA144614921 PubChem:127151 PubChem:46504845 RxCUI: 60842 Therapeutic Targets Database: DAP000720 Wikipedia: Reboxetine ZINC: ZINC000003996032