N-[2-(4-Methoxypiperidin-1-Yl)pyrimidin-4-Yl]-2-(1h-Pyrazol-4-Yl)-3h-Imidazo[4,5-C]pyridin-6-Amine

InChIKey	`CBLSWPLVIPVELR-UHFFFAOYSA-N`
Compound Name	N-[2-(4-Methoxypiperidin-1-Yl)pyrimidin-4-Yl]-2-(1h-Pyrazol-4-Yl)-3h-Imidazo[4,5-C]pyridin-6-Amine
Canonical SMILES	`COC1CCN(c2nccc(Nc3cc4[nH]c(-c5cn[nH]c5)nc4cn3)n2)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.15
Source	BindingDB;ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	7.2	Ki	ChEMBL
P04626	ERBB2	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	7.2	Ki	BindingDB
P24941	CDK2	Homo sapiens	Human	PF00069	7.0	IC50	ChEMBL;BindingDB