InChIKey	CBGUOGMQLZIXBE-XGQKBEPLSA-N
Compound Name	Clobetasol Propionate
Canonical SMILES	CCC(=O)O[C@]1(C(=O)CCl)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.6
Source	ChEMBL;BindingDB

DrugBank ID	DB01013
Drug Name	Clobetasol propionate
CAS Number	25122-46-7
Groups	approved investigational
ATC Codes	nan
Description	Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors.[L11815] It has demonstrated superior activity compared to [fluocinonide][A190963] and was first described in the literature in 1974.[A190936] Clobetasol Propionat...

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Categories: Adrenal Cortex Hormones Anti-Inflammatory Agents Corticosteroids Cytochrome P-450 CYP3A Inducers Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inducers Cytochrome P-450 CYP3A4 Inducers (strength unknown) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A5 Inducers Cytochrome P-450 CYP3A5 Inducers (strength unknown) Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Substrates Fused-Ring Compounds Glucocorticoids Hormones Hormones, Hormone Substitutes, and Hormone Antagonists Hyperglycemia-Associated Agents Immunosuppressive Agents Pregnadienes Pregnadienetriols Pregnanes Steroids Steroids, Fluorinated Thyroxine-binding globulin inhibitors

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Cross-references: BindingDB: 39347 ChEBI: 31414 CHEMBL1159650 ChemSpider: 30399 Drugs Product Database (DPD): 7558 D01272 PDB: XRD PharmGKB: PA164744375 PubChem:32798 PubChem:46505670 RxCUI: 21245 Therapeutic Targets Database: DAP001183 Wikipedia: Clobetasol_propionate ZINC: ZINC000003977767