Molecule Details
| InChIKey | CAXQFRKUUBOXBI-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[3-(2,3-dibromo-5-oxo-6H-imidazo[1,2-d][1,2,4]triazin-8-yl)phenyl]butane-1-sulfonamide |
| Canonical SMILES | CCCCS(=O)(=O)Nc1cccc(-c2nnc(O)n3c(Br)c(Br)nc23)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.86 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P54750 | PDE1A | Homo sapiens | Human | PF00233 PF08499 | 7.1 | IC50 | ChEMBL |
| Q01064 | PDE1B | Homo sapiens | Human | PF00233 PF08499 | 7.1 | IC50 | ChEMBL;BindingDB |
| Q14123 | PDE1C | Homo sapiens | Human | PF00233 PF08499 | 7.1 | IC50 | ChEMBL |
| Q13370 | PDE3B | Homo sapiens | Human | PF00233 | 6.5 | IC50 | ChEMBL |
| Q14432 | PDE3A | Homo sapiens | Human | PF00233 | 6.5 | IC50 | ChEMBL;BindingDB |