Molecule Details
InChIKeyCALAEFSQWBJMDU-UHFFFAOYSA-N
Compound Namen-Cyclohexyl-2-(1h-indazol-5-yl)imidazo[1,2-a]pyrimidin-3-amine
Canonical SMILESc1cnc2nc(-c3ccc4[nH]ncc4c3)c(NC3CCCCC3)n2c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)21
Pfam Stratification Cross-Family
Avg pChEMBL6.81
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (21)
Target Gene Organism Category Pfam pChEMBL Type Source
P49841 GSK3B Homo sapiens Human PF00069 8.0 Ki ChEMBL;BindingDB
Q9HAZ1 CLK4 Homo sapiens Human PF00069 8.0 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 7.9 Ki ChEMBL
Q13237 PRKG2 Homo sapiens Human PF00027 PF00069 7.6 Ki ChEMBL
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 7.6 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 7.5 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 7.2 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.6 Ki ChEMBL;BindingDB
P17612 PRKACA Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.6 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.5 Ki ChEMBL;BindingDB
P68400 CSNK2A1 Homo sapiens Human PF00069 6.5 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.4 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.3 Ki ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 6.3 Ki ChEMBL
P07332 FES Homo sapiens Human PF00611 PF07714 PF00017 6.2 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q9Y6M4 CSNK1G3 Homo sapiens Human PF12605 PF00069 6.1 Ki ChEMBL