Molecule Details
| InChIKey | CAILNONEKASNSH-UHFFFAOYSA-N |
|---|---|
| Compound Name | Cathepsin L Inhibitor I |
| Canonical SMILES | O=C(NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)CF)OCc1ccccc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.05 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P07711 | CTSL | Homo sapiens | Human | PF08246 PF00112 | 8.2 | IC50 | ChEMBL;BindingDB |
| P07858 | CTSB | Homo sapiens | Human | PF00112 PF08127 | 7.2 | IC50 | ChEMBL;BindingDB |
| P07384 | CAPN1 | Homo sapiens | Human | PF01067 PF13833 PF00648 | 6.4 | IC50 | BindingDB |
| P17655 | CAPN2 | Homo sapiens | Human | PF01067 PF13833 PF00648 | 6.4 | IC50 | BindingDB |