4-(4-(4-(4-(dimethylamino)phenyl)-4-oxobutoxy)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide

InChIKey	`CADOQGNFDXDEHI-UHFFFAOYSA-N`
Compound Name	4-(4-(4-(4-(dimethylamino)phenyl)-4-oxobutoxy)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide
Canonical SMILES	`CN(C)c1ccc(C(=O)CCCOc2ccc(S(=O)(=O)C3(C(=O)NO)CCOCC3)cc2)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	7.99
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P45452	MMP13	Homo sapiens	Human	PF00045 PF00413 PF01471	9.7	IC50	ChEMBL;BindingDB
P08253	MMP2	Homo sapiens	Human	PF00040 PF00045 PF00413	7.7	pIC50	TTD_MultiTarget
P22894	MMP8	Homo sapiens	Human	PF00045 PF00413 PF01471	6.8	IC50	ChEMBL;BindingDB
P14780	MMP9	Homo sapiens	Human	PF00040 PF00045 PF00413	6.0	IC50	ChEMBL;BindingDB
P18843	nadE	Escherichia coli (strain K12)	Pathogen	PF02540	9.7	pIC50	TTD_MultiTarget