Molecule Details
InChIKeyCACMTVGXYAZZNY-UHFFFAOYSA-N
Compound Name6-{[(5-Cyanopyrazin-2-Yl)carbamoyl]amino}naphthalene-2-Carboxylic Acid
Canonical SMILESN#Cc1cnc(NC(=O)Nc2ccc3cc(C(=O)O)ccc3c2)cn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)11
Pfam Stratification Cross-Family
Avg pChEMBL6.46
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
O14757 CHEK1 Homo sapiens Human PF00069 6.9 Ki ChEMBL;BindingDB
P68400 CSNK2A1 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.6 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.5 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.4 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
Q86V86 PIM3 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q96SB4 SRPK1 Homo sapiens Human PF00069 6.1 Ki ChEMBL