Molecule Details
| InChIKey | CABBMMXFOOZVMS-PMERELPUSA-N |
|---|---|
| Compound Name | GI-181771X |
| Canonical SMILES | CC(C)N(C(=O)CN1C(=O)[C@H](NC(=O)Nc2cccc(C(=O)O)c2)C(=O)N(c2ccccc2)c2ccccc21)c1ccccc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.57 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB12309 |
|---|---|
| Drug Name | GI-181771X |
| CAS Number | 305366-98-7 |
| Groups | experimental |
| ATC Codes | nan |
| Description | Gski181771 X is under investigation in clinical trial NCT00600743 (Effect of a CCK-1R Agonist on Food Intake in Humans). |
Categories: Benzazepines Heterocyclic Compounds, Fused-Ring Receptor, Cholecystokinin A, agonists
Cross-references: BindingDB: 50329178 CHEMBL1269257 ChemSpider: 26362988 PubChem:51353551 PubChem:347828574
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P32238 | CCKAR | Cholecystokinin receptor type A | agonist | targets |