Molecule Details
InChIKeyBZSUCLDZAQTFQJ-MSOLQXFVSA-N
Compound Name(16R,17S)-16,17-dihydroxy-4,14,19-triazaheptacyclo[12.11.2.02,6.07,27.08,13.019,26.020,25]heptacosa-1,6,8,10,12,20,22,24,26-nonaen-3-one
Canonical SMILESO=C1NCc2c1c1c3ccccc3n3c1c1c2c2ccccc2n1C[C@@H](O)[C@@H](O)C3
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)4
Pfam Stratification Cross-Family
Avg pChEMBL6.9
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (4)
Target Gene Organism Category Pfam pChEMBL Type Source
P52333 JAK3 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 8.2 IC50 ChEMBL;BindingDB
P43403 ZAP70 Homo sapiens Human PF07714 PF00017 6.7 IC50 ChEMBL;BindingDB
P43405 SYK Homo sapiens Human PF07714 PF00017 6.5 IC50 ChEMBL;BindingDB
P42229 STAT5A Homo sapiens Human PF00017 PF01017 PF02864 PF02865 PF21354 6.2 IC50 ChEMBL;BindingDB