Molecule Details
InChIKeyBZFGDXJGWSIYQP-UHFFFAOYSA-N
Compound Name2-(4-Amino-3-iodopyrazolo[3,4-d]pyrimidin-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Canonical SMILESNc1ncnc2c1c(I)nn2C1OC(CO)C(O)C1O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.23
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.5 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.4 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.1 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.1 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.0 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 6.0 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.0 Ki ChEMBL