Molecule Details
InChIKeyBYPMJBXPNZMNQD-PZJWPPBQSA-N
Compound NameZicronapine
Canonical SMILESCN1CCN([C@@H]2C[C@@H](c3ccccc3)c3ccc(Cl)cc32)CC1(C)C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL9.12
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12188
Drug NameZicronapine
CAS Number170381-16-5
Groups investigational
ATC Codes nan
DescriptionZicronapine has been used in trials studying the treatment of Schizophrenia.

Cross-references: CHEMBL3039528 ChemSpider: 9640456 PubChem:11465618 PubChem:347828474 Wikipedia: Zicronapine
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P21728 DRD1 Homo sapiens Human PF00001 9.9 Ki ChEMBL;BindingDB
P28223 HTR2A Homo sapiens Human PF00001 9.3 IC50 BindingDB
P14416 DRD2 Homo sapiens Human PF00001 8.1 Ki ChEMBL;BindingDB
DrugBank Target Actions (3)
Target Gene Target Name Action Type
P14416 DRD2 D(2) dopamine receptor modulator targets
P21728 DRD1 D(1A) dopamine receptor modulator targets
P28223 HTR2A 5-hydroxytryptamine receptor 2A modulator targets