Molecule Details
| InChIKey | BYKMCJLDXBMWTO-UHFFFAOYSA-N |
|---|---|
| Compound Name | 5-(3-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)isoxazole-3-carboxamide |
| Canonical SMILES | Nc1cccc(-c2cc(C(=O)NCCCCCCC(=O)NO)no2)c1 |
| Clinical Status | Clinical Multi-Target |
| Targets (Human+Pathogen) | 7 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.82 |
| Source | ChEMBL;BindingDB;TTD_MultiTarget |
2D Structure
Activity Profile
Target Activities (7)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9UBN7 | HDAC6 | Homo sapiens | Human | PF00850 PF02148 | 8.6 | IC50 | ChEMBL;BindingDB |
| O15379 | HDAC3 | Homo sapiens | Human | PF00850 | 8.4 | IC50 | ChEMBL;BindingDB |
| Q02161 | RHD | Homo sapiens | Human | PF00909 | 8.1 | pIC50 | TTD_MultiTarget |
| Q92769 | HDAC2 | Homo sapiens | Human | PF00850 | 8.1 | pIC50 | TTD_MultiTarget |
| Q969S8 | HDAC10 | Homo sapiens | Human | PF00850 | 7.8 | IC50 | ChEMBL;BindingDB |
| Q13547 | HDAC1 | Homo sapiens | Human | PF00850 | 7.7 | pIC50 | TTD_MultiTarget |
| Q9BY41 | HDAC8 | Homo sapiens | Human | PF00850 | 6.0 | IC50 | ChEMBL;BindingDB |