InChIKey	BYBLEWFAAKGYCD-UHFFFAOYSA-N
Compound Name	Miconazole
Canonical SMILES	Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	16
Pfam Stratification	Cross-Family
Avg pChEMBL	6.57
Source	ChEMBL;TTD_MultiTarget

DrugBank ID	DB01110
Drug Name	Miconazole
CAS Number	22916-47-8
Groups	approved investigational vet_approved
ATC Codes	A07AC01 J02AB01 D01AC52 G01AF20 A01AB09 D01AC02 S02AA13 G01AF04
Description	Miconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well.[A203636] It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole is no longer available, a wide variety of suppositories...

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Categories: 14-alpha Demethylase Inhibitors Anti-Infective Agents Antifungal Agents Antifungal Agents (Vaginal) Antifungals for Dermatological Use Antifungals for Topical Use Antiinfectives and Antiseptics for Local Oral Treatment Azole Antifungals Chemically-Induced Disorders Cytochrome P-450 CYP2A6 Inhibitors Cytochrome P-450 CYP2A6 Inhibitors (strong) Cytochrome P-450 CYP2B6 Inhibitors Cytochrome P-450 CYP2B6 Inhibitors (strength unknown) Cytochrome P-450 CYP2C19 Inhibitors Cytochrome P-450 CYP2C19 Inhibitors (strong) Cytochrome P-450 CYP2C8 Inhibitors Cytochrome P-450 CYP2C8 Inhibitors (strength unknown) Cytochrome P-450 CYP2C9 Inhibitors Cytochrome P-450 CYP2C9 Inhibitors (moderate) Cytochrome P-450 CYP2C9 Inhibitors (strong) Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) Cytochrome P-450 CYP2E1 Inhibitors Cytochrome P-450 CYP2E1 Inhibitors (strong) Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (moderate) Cytochrome P-450 Enzyme Inhibitors Dermatologicals Enzyme Inhibitors Genito Urinary System and Sex Hormones Gynecological Antiinfectives and Antiseptics Hormone Antagonists Hormones, Hormone Substitutes, and Hormone Antagonists Imidazole Derivatives Imidazole and Triazole Derivatives Imidazoles Intestinal Antiinfectives Otologicals P-glycoprotein inhibitors Sensory Organs Steroid Synthesis Inhibitors Stomatological Preparations Vaginal Creams, Foams, and Jellies

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Cross-references: BindingDB: 31772 ChEBI: 82892 CHEMBL91 ChemSpider: 4044 Drugs Product Database (DPD): 2373 Guide to Pharmacology: 2449 IUPHAR: 2449 C08070 D00882 PharmGKB: PA450494 PubChem:4189 PubChem:46506017 RxCUI: 6932 Therapeutic Targets Database: DAP000154 Wikipedia: Miconazole