Molecule Details
| InChIKey | BYBLEWFAAKGYCD-SFHVURJKSA-N |
|---|---|
| Compound Name | (R)-Miconazole |
| Canonical SMILES | Clc1ccc(CO[C@@H](Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 9 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.0 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (9)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P33261 | CYP2C19 | Homo sapiens | Human | PF00067 | 10.7 | IC50 | BindingDB |
| P08684 | CYP3A4 | Homo sapiens | Human | PF00067 | 6.7 | IC50 | BindingDB |
| Q16850 | CYP51A1 | Homo sapiens | Human | PF00067 | 6.7 | IC50 | BindingDB |
| P05093 | CYP17A1 | Homo sapiens | Human | PF00067 | 6.6 | Ki | BindingDB |
| P11511 | CYP19A1 | Homo sapiens | Human | PF00067 | 6.2 | IC50 | BindingDB |
| P51589 | CYP2J2 | Homo sapiens | Human | PF00067 | 6.2 | IC50 | BindingDB |
| P9WPP7 | cyp121 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Pathogen | PF00067 | 7.1 | Kd | BindingDB |
| P9WPP8 | cyp51 | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) | Pathogen | PF00067 | 6.7 | Kd | BindingDB |
| P9WPL0 | cyp144 | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) | Pathogen | PF00067 | 6.0 | Kd | BindingDB |