Molecule Details
| InChIKey | BWVJYTGTOWKCOX-UHFFFAOYSA-N |
|---|---|
| Compound Name | 6,8-Dimethoxy-3-methyl-1-(2-methyl-3-pyridinyl)imidazo[5,1-c][1,2,4]benzotriazine |
| Canonical SMILES | COc1cc(OC)c2nnc3c(C)nc(-c4cccnc4C)n3c2c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 8 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.68 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (8)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9Y233 | PDE10A | Homo sapiens | Human | PF01590 PF00233 | 8.8 | IC50 | ChEMBL;BindingDB |
| O00408 | PDE2A | Homo sapiens | Human | PF01590 PF00233 | 6.7 | IC50 | ChEMBL |
| O43924 | PDE6D | Homo sapiens | Human | PF05351 | 6.3 | IC50 | ChEMBL |
| P16499 | PDE6A | Homo sapiens | Human | PF01590 PF00233 | 6.3 | IC50 | ChEMBL |
| P18545 | PDE6G | Homo sapiens | Human | PF04868 | 6.3 | IC50 | ChEMBL |
| P35913 | PDE6B | Homo sapiens | Human | PF01590 PF00233 | 6.3 | IC50 | ChEMBL |
| P51160 | PDE6C | Homo sapiens | Human | PF01590 PF00233 | 6.3 | IC50 | ChEMBL |
| Q13956 | PDE6H | Homo sapiens | Human | PF04868 | 6.3 | IC50 | ChEMBL |