Molecule Details
InChIKeyBWQAQACZKDLJAW-OAQYLSRUSA-N
Compound NameShp2-IN-23
Canonical SMILESNc1nccc(Sc2ccc3nc(N4CCC5(CC4)Cc4ncccc4[C@H]5N)cnc3n2)c1Cl
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL8.01
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P27361 MAPK3 Homo sapiens Human PF00069 8.3 IC50 ChEMBL
P28482 MAPK1 Homo sapiens Human PF00069 8.3 IC50 ChEMBL
Q06124 PTPN11 Homo sapiens Human PF00017 PF00102 7.4 IC50 ChEMBL