Molecule Details
InChIKeyBTSCZNWXJQSJIE-UHFFFAOYSA-N
Compound NameN,N-dimethyl-1-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)methanamine
Canonical SMILESCN(C)CC1CC2c3ccccc3Cc3ccccc3N2O1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)10
Pfam Stratification Homologous
Avg pChEMBL6.83
SourceChEMBL;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
P35367 HRH1 Homo sapiens Human PF00001 8.2 IC50 ChEMBL
P28335 HTR2C Homo sapiens Human PF00001 7.9 IC50 ChEMBL
P28223 HTR2A Homo sapiens Human PF00001 7.6 IC50 ChEMBL
P21917 DRD4 Homo sapiens Human PF00001 6.9 IC50 ChEMBL
P35462 DRD3 Homo sapiens Human PF00001 6.8 IC50 ChEMBL
P08913 ADRA2A Homo sapiens Human PF00001 6.4 IC50 ChEMBL
P35348 ADRA1A Homo sapiens Human PF00001 6.3 pIC50 TTD_MultiTarget
P28221 HTR1D Homo sapiens Human PF00001 6.2 IC50 ChEMBL
P14416 DRD2 Homo sapiens Human PF00001 6.1 IC50 ChEMBL
P08908 HTR1A Homo sapiens Human PF00001 6.0 IC50 ChEMBL